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Environment inside brain cells holds clues to protein aggregation

Gene expression inside Parkinson’s disease patient’s brain cells seems to trigger structural changes of the Parkinson-linked protein alpha-synuclein. This was discovered when MultiPark researchers converted skin cells from Parkinson patients into midbrain cells in the dish. The study was published in Acta Neuropathologica Communications. Parkinson’s disease (PD) is a neurodegenerative disorder lin

https://www.multipark.lu.se/article/environment-inside-brain-cells-holds-clues-protein-aggregation - 2025-09-29

Ph.D. defence interview - Emil Ygland

Emil Ygland Rödström is defending his thesis on the 20th of November. His research is about clinical, genetical, and biochemical biomarkers for the prognosis of Parkinson’s disease patients. Here, he tells us more about the discoveries and his time as a Ph.D. student in the Clinical Neurogenetics group at MultiPark. What is your research about? My thesis work consists of two different parts. In th

https://www.multipark.lu.se/article/phd-defence-interview-emil-ygland - 2025-09-29

Faster and better treatment for Parkinson’s disease with the Manage PD tool

Presently many of Sweden’s 20,000 Parkinson’s patients are not receiving the treatment they need, and many of the most seriously ill receive incorrect or inappropriate therapy. With the new Manage PD tool and the PD Pal study, Per Odin, professor at Lund University and senior attending physician at Skåne University Hospital in Lund, hopes to be able to improve the care of Parkinson’s patients. Eve

https://www.multipark.lu.se/article/faster-and-better-treatment-parkinsons-disease-manage-pd-tool - 2025-09-29

The majority of the most cited researchers at Lund University belong to MultiPark

Three out of Lund University’s four most cited scientists are research leaders at MultiPark, according to Clarivate’s report for this year. The highly anticipated annual list identifies researchers who demonstrated significant influence in their chosen field or fields through the publication of multiple highly cited papers during the last decade. Their names are drawn from the publications that ra

https://www.multipark.lu.se/article/majority-most-cited-researchers-lund-university-belong-multipark - 2025-09-29

Ph.D. defence interview - Alexander Svanbergsson

During his Ph.D. studies, Alexander Svanbergsson has established a modelling system to screen for factors affecting the aggregation of alpha-synuclein in Parkinson’s disease. On the 3rd of December, it is time for him to defend his work supervised by Prof. Jia-Yi Li. Now, Alexander tells us about his research in the research group Neural Plasticity and Repair at MultiPark. What is your research ab

https://www.multipark.lu.se/article/phd-defence-interview-alexander-svanbergsson - 2025-09-29

Common skin bacteria may trigger aggregation of Parkinson’s disease protein

Peptides from the common bacteria Staphylococcus aureus speed up the pathological aggregation of α-synuclein, a protein linked to Parkinson’s disease. This was discovered by researchers at MultiPark and published in the International Journal of Molecular Sciences. Staphylococcus aureus is carried by 30–70% of the general population as a commensal bacterium. It produces a special kind of peptides c

https://www.multipark.lu.se/article/common-skin-bacteria-may-trigger-aggregation-parkinsons-disease-protein - 2025-09-29

Ph.D. defence interview - Laura Andreoli

Ph.D. student Laura Andreoli spent several years digging into the neural pathways involved in involuntary movements in Parkinson’s disease. On the 14th of December, she defends her thesis. And she is eager to share her findings and thoughts about her time in the Basal Ganglia Pathophysiology Lab headed by MultiPark’s coordinator Angela Cenci Nilsson. Tell us about your research! Most patients suff

https://www.multipark.lu.se/article/phd-defence-interview-laura-andreoli - 2025-09-29

MoRe-Lab opens the gates

MoRe-Lab (Movement & Reality Lab) is an experimental health science test environment for studies of movement, activity, and behavior in full scale. A new platform for interdisciplinary collaborations opens to the entire university. Initiators and partners outside the academy are also welcome to join MoRe-Lab's operations. On December 8th, MoRe-Lab will be inaugurated. On Wednesday, December 8th, M

https://www.multipark.lu.se/article/more-lab-opens-gates - 2025-09-29

Large EU project on Alzheimer's coordinated by Lund University

With the support of an EU grant of 1.9 million euros, Alzheimer's researcher Oskar Hansson will lead and coordinate a research collaboration between Sweden, Spain, France, Germany and Denmark. The goal is to create conditions for early and correct diagnosis of Alzheimer's disease. This is to improve the treatment and care of the patients and reduce the societal costs that the disease causes. The i

https://www.multipark.lu.se/article/large-eu-project-alzheimers-coordinated-lund-university - 2025-09-29

Ph.D. defence interview - Lina Rosengren

Lina Rosengren explores factors for maintaining life satisfaction despite suffering from Parkinson’s disease. December 17, she defends her Ph.D. projects supervised by Prof. Jan Lexell. Lina explains her most important findings, future directions, and time as a Ph.D. student in the Rehabilitation Medicine group at MultiPark. Tell us about your research! I work part-time as a physician in Rehabilit

https://www.multipark.lu.se/article/phd-defence-interview-lina-rosengren - 2025-09-29

Distinguished professorship to Malin Parmar

The research group leader Malin Parmar is granted 50 million SEK over 10 years within the Distinguished professor program by the Swedish Research Council. The purpose of the Distinguished Professor Program is to create conditions for the most prominent researchers to conduct long-term, innovative research with great potential to achieve scientific breakthroughs. Malin Parmar is Professor of cellul

https://www.multipark.lu.se/article/distinguished-professorship-malin-parmar - 2025-09-29

Daniella Rylander Ottosson has been admitted a Wallenberg Academy Fellow

The career program Wallenberg Academy Fellows is the largest private investment in young researchers in Sweden. It provides the most promising young researchers with long-term resources, giving them excellent opportunities to establish themselves and build up their research groups. Wallenberg Academy Fellows is designed for young researchers and was launched by the Knut and Alice Wallenberg Founda

https://www.multipark.lu.se/article/daniella-rylander-ottosson-has-been-admitted-wallenberg-academy-fellow - 2025-09-29

MultiPark is investing in Artificial Intelligence

From January 2022, MultiPark will have its own coordinator for projects involving Artificial Intelligence. Pär Halje is an assistant researcher in Per Petersson’s Integrative Neurophysiology and Neurotechnology group. For a one year trial period, he will spend 20 % of his time facilitating the implementation of artificial intelligence (AI) tools in all-day methods used in MultiPark’s research grou

https://www.multipark.lu.se/article/multipark-investing-artificial-intelligence - 2025-09-29

Season Greetings from the coordinator

The best of MultiPark 2021 and looking forward to 2022. As 2021 turns towards its end, we can look back on the many positive events we managed to land together this year. In particular, We have awarded salary support for Ph.D. students and young group leaders, which has broadly benefitted our community. We have formed a networking group composed of young researchers (the “Young MultiParkers”) with

https://www.multipark.lu.se/article/season-greetings-coordinator - 2025-09-29

Human midbrain organoids grown in silk recapitulate midbrain development and support functionally mature dopamine neurons

In their latest study, published in Nature Communications, the Parmar Lab has established midbrain organoids using silk microfibers as scaffolds, offering a refined in vitro model of human midbrain development. They have studied their silk midbrain organoids using single cell sequencing, proteomics and functional assessment in order to shed light on the developmental trajectory, maturation and sub

https://www.multipark.lu.se/article/human-midbrain-organoids-grown-silk-recapitulate-midbrain-development-and-support-functionally - 2025-09-29

Ph.D. defence interview - Elin Byman

During her thesis project, Elin Byman discovered a role of alpha-amylase in Alzheimer’s disease. January 21, she defends her Ph.D. work supervised by Malin Wennström in the Preclinical memory research group at MultiPark. Here, she tells about the journey and major breakthroughs. Tell us about your research! The enzyme alpha-amylase has long been known to be abundant in saliva and the gastrointesti

https://www.multipark.lu.se/article/phd-defence-interview-elin-byman - 2025-09-29

Ph.D. defence interview - Sabine Konings

Sabine Konings’ Ph.D. project sheds light on the role of different genetic variants of apolipoprotein E in early Alzheimer’s disease development. January 27, she defends her thesis. In this interview, she shares the most important findings as a Ph.D. student in the Experimental Dementia group. Tell us about your research! Apolipoprotein E4 (ApoE4) is the major genetic risk factor for developing la

https://www.multipark.lu.se/article/phd-defence-interview-sabine-konings - 2025-09-29

eScience for translational movement analysis

MultiPark leads one of the four projects recently selected by Lund University to pursue emerging research topics. The project eSCIENCE MOVES will apply artificial intelligence and machine learning to achieve new definitions of motor alterations in patients affected by Parkinson´s disease as well as rodent models of human parkinsonian features. Movement is the visible output of neuronal pathways li

https://www.multipark.lu.se/article/escience-translational-movement-analysis - 2025-09-29

Working groups – renovation in progress

The PI retreat in January resulted in a groundbreaking decision: MultiPark’s working groups should be replaced by a more dynamic organization including both "special interest groups” and “task force groups”. Here is what will happen. Discussing the MultiPark seven translational working groups was an important point in the agenda of the PI member retreat in January. Already while planning for the m

https://www.multipark.lu.se/article/working-groups-renovation-progress - 2025-09-29

Ph.D. defence interview - Caroline Haikal

During her Ph.D. studies, Caroline Haikal has investigated the connections between the gut and the brain in early Parkinson’s disease development. On March 11, she defends her work supervised by Prof. Jia-Yi Li. Here, Caroline tells us about her research in Neural Plasticity and Repair, one of MultiPark’s experimental research groups. Tell us about your research! My research is about the connectio

https://www.multipark.lu.se/article/phd-defence-interview-caroline-haikal - 2025-09-29